孙文武

个人信息：

出生年月：1985年12月

民族：汉族

职称：讲师、硕士生导师

研究方向：有机合成方法学、药物合成化学

电子邮箱：wenwusun@scuec.edu.cn

学习与工作经历

2016.07-至今 中南民族大学药学院讲师

2013.09-2016.06 中国科学院大学昆明植物研究所博士

2011.01-2013.08 中国科学院大学昆明植物研究所助理研究员

科研项目:

4.中央高校基本科研业务费专项资金项目，CZQ21018,新型多组分去芳构化反应构建多取代稠环核苷化合物及其生物活性研究，2021/04-2023/04，结题，主持

3.中央高校基本科研业务费专项资金项目，CZQ17009，无金属参与的醇氧化反应研究，2017/01-2018/12,结题，主持

2.国家自然科学基金面上项目，GZY17002，钯催化的碳-碳键活化构建氮杂环化合物的反应研究，2018.01-2022.12，结题，参与（排2）

1.国家自然科学基金面上项目，GZY14012，惰性sp³碳-氢键活化构建氮杂环骨架的方法学研究及其在合成中的应用，2015.01-2018.12，结题，参与（排2）

研究论文：

24. Yuenian Xu, Yan Zhang, Yong Liu,Wen-Wu Sun, Jie Huang, Hui He, Yingjie Wu, Wen Liu, Shao-Fei Ni*, Xu-Qiong Xiao, Xinxin Shao*. Bioinspired zinc-mediated umpolung thiolation of alkyl electrophiles: reaction development, scope and mechanism.Science China Chemistry, 2024, 67, 898−907.(一区TOP)

23. Jie Huang, Jin-Quan Li, Xin-Yue Cui, Yi-Han Qin, Shi-Jie Ma, Zi-An An,Wen-Wu Sun,* and Bin Wu*. A Method for the Synthesis of Thioindoles through Copper-Catalyzed C−S Bond Coupling Reaction.The Journal of Organic Chemistry, 2024, 89, 245−256 (二区)

22.Wen-Wu Sun*,Yi-Bing Xie,Ting-Ting Deng, Ji-Kai Liu and Bin Wu*. Acid-promoted cyclization reaction of the guanine base with 1,1,3,3-tetramethoxypropane: A method for the preparation of M₁dG and its derivatives.Current Protocols,2023, 3, e741.(Invited Paper)

21.Shuo Wang⁽¹⁾(本科生), Shi-Jie Ma⁽¹⁾, Ji-Cong Lou,Wen-Wu Sun*, and Bin Wu*. Copper-catalyzed [3 + 2] cycloaddition reaction of N-hydroxysuccinimide ester with isocyanoacetates for the synthesis of 4,5-disubstituted oxazoles.The Journal of Organic Chemistry, 2023, 88, 4481−4493 (二区TOP)

20. Jie Huang,Wen-Wu Sun,* Jin-Quan Li, Ao-Di Ma, Ji-Kai Liu,* and Bin Wu*. Copper-catalyzed C2- or C3-thioglycosylation of indoles with N‑(thioglycosides)succinimides: An effective strategy for the total synthesis of isatindigotindolosides.OrganicLetters, 2023, 25(43), 528−532. (自然指数期刊,一区TOP)

19. Ting-Ting Deng⁽¹⁾, Yi-Bing Xie⁽¹⁾(本科生),Wen-Wu Sun*, Jie Huang, Ting-Ting He, Ji-Kai Liu,* and Bin Wu*. Synthesis of nucleoside and nucleotide analogues by cyclization of the guanine base with 1,1,3,3-tetramethoxypropane.OrganicLetters, 2022, 24(42): 7834−7838. (自然指数期刊,一区TOP)

18. Na Chen(本科生), Ting-Ting Deng, Jin-Quan Li, Xin-Yue Cui,Wen-Wu Sun*, and Bin Wu*. Hypervalent iodine(III)-mediated umpolung dialkoxylation ofN‑substituted indoles.The Journal of Organic Chemistry, 2022, 87(19), 12759−12771.(二区TOP)

17. Ting-Ting Deng⁽¹⁾, Jie Huang⁽¹⁾, Guo Lian,Wen-Wu Sun*, Bin Wu*. Pd(II)-catalyzed carbonylative cyclization of N-aryl-2-aminopyrimidines with Mo(CO)₆as carbon monoxide source.Asian Journal of Organic Chemistry,2021, 10 (11), 2880-2882.(三区)

16. Ya-Lan Li⁽¹⁾, Jin-Yu Pang⁽¹⁾, Ji-Cong Lou,Wen-Wu Sun*, Ji-Kai Liu*, Bin Wu*. Chemo‐ and site-selective Fischer esterification catalyzed by B(C₆F₅)₃.Asian Journal of Organic Chemistry, 2021, 10(6): 1424-1427.(三区)

15.Wen-Wu Sun*, Na Chen(本科生), Ting-Ting Wei, Guo-Jing You, Hao Yang, Ji-Kai Liu*, Bin Wu*. Environmentally friendly protocol for 2,3-difunctionlization of indole derivatives.The Journal of Organic Chemistry, 2020, 85, 10143−10151.(二区TOP)

14.Zi-Long Bian,Xin-Xin Lv,Ya-Lan Li,Wen-Wu Sun*,Ji-Kai Liu*,Bin Wu*.Acid-promoted synthesis and photophysical properties of substituted acridine derivatives.Organic & Biomolecular Chemistry, 2020, 18, 8141-8146.(三区)

13.Wen-Wu Sun, Ji-Kai Liu*, Bin Wu*. Practical synthesis of polysubstituted unsymmetric 1,10-phenanthrolines by palladium catalyzed intramolecular oxidative cross coupling of C(sp²)–H and C(sp³)–H bonds of carboxamides.Organic Chemistry Frontiers, 2019, 6, 544-550. (一区TOP)

12. Ji-Cong Lou, Jian-Ye Li,Wen-Wu Sun*, Bin Wu*. Metal-free oxidation of trichloroacetimidates to aldehydes.Asian Journal of Organic Chemistry, 2019, 8, 265-268. (三区)

11. Jian-Ye Li, Jun Huang, Shi-Jin Zhang, Chunna Yao,Wen-Wu Sun*, Bin Liu*, Yingbi Zhou*, Bin Wu*.Synthesis of diaryl sulfides through C-H bond functionalization of arylamides with cobalt salt and elemental sulfur.Tetrahedron Letters, 2019, 60, 895–899. (三区)

10. Dong-Dong Xu⁽¹⁾,Wen-Wu Sun⁽¹⁾, Yan-Li Xie, Ji-Kai Liu*, Bin Liu*, Ying-Bi Zhou* Bin Wu*. Metal-free regioselective hypervalent iodine-mediated C-2 and C-3 difunctionalization ofN‑substituted indoles.The Journal of Organic Chemistry, 2016, 81, 11081-11094. (二区TOP)

9. Shi-Jin Zhang⁽¹⁾,Wen-Wu Sun⁽¹⁾, Pei Cao*, Xiao-Ping Dong*, Ji-Kai Liu, Bin Wu*. Stereoselective synthesis of diazabicyclicβ-lactams through intramolecular amination of unactivated C(sp³)-H bonds of carboxamides by palladium catalysis.The Journal of Organic Chemistry, 2016, 81, 956-968.(二区TOP)

8.Wen-Wu Sun, Pei Cao, Ren-Qiang Mei, Yue Li, Yuan-Liang Ma, Bin Wu*. Palladium-catalyzed unactivated C(sp³)-H bond activation and intramolecular amination of carboxamides: a new approach toβ‑lactams.Organic Letters, 2014, 16, 480-483. (一区TOP)

7.Wen-Wu Sun, Qing-Rong Cheng, Hong Zhou*, Zhi-Quan Pan*. Syntheses, crystal structures, and properties of Cu(II) and Zn(II) complexes with an asymmetric tripodal ligand.Journal of Coordination Chemistry, 2013, 66, 56-65. (四区)

6.Wen-Wu Sun, Shi-Rong Li, Hong Zhou*, Zhi-Quan Pan*, Qi-Mao Huang, Xue-Lei Hu. Assembly of a novel dumbbell-type dinuclear copper(II) complex: Synthesis, structure and properties.Zeitschrift für anorganische und allgemeine Chemie, 2010, 636, 1386–1391. (四区)

5. Zhang Shi-Jin,Wen-WuSun, Yu Qun-Ying, Pei Cao, Xiao-Ping Dong, Bin Wu*. Stereoselective synthesis of (-)-3-ppp through palladium-catalysed unactivated C(sp³)-H arylation at the C-3 position of l-pipecolinic acid.Tetrahedron Letters, 2017, 58(7): 606-609.(三区)

4. Yan-Li Xie, Dong-Dong Xu,Wen-Wu Sun, Shi-Jin Zhang, Xiao-Ping Dong, Bin Liu*, Ying-Bi Zhou*, Bin Wu*. Cobalt-catalyzed oxidative dimerization of 2-phenylpyridine derivatives.Asian Journal of Organic Chemistry. 2016, 5, 961-965. (三区)

3. Qun-Ying Yu, Hong-Ming Zhong,Wen-Wu Sun, Shi-Jin Zhang, Pei Cao*, Xiao-Ping Dong, Hong-Bo Qin, Ji-Kai Liu, Bin Wu*. Palladium-catalyzed C(sp³)-H functionalization at the C(3) position of l-pipecolinic acid derivatives.Asian Journal of Organic Chemistry. 2016, 5, 608 – 612. (三区)

2. Pei Cao, Zhen-Jie Li,Wen-Wu Sun, Shashwat Malhotra, Yuan-Liang Ma, Bin Wu*, Virinder S. Parmar. CascadeN-alkylation/hemiacetalization for facile construction of the spiroketal skeleton of acortatarin alkaloids with therapeutic potentiality in diabetic nephropathy.Natural Products and Bioprospecting. 2015, 5, 37–45. (四区)

1. Hong Zhou*, Xiao-Hong Chen,Wen-Wu Sun, Yu Mei, Zhi-Quan Pan*. A unique coordination polymer with tetranuclear nickel(II) units linked by macrocyclic ligands.RSC Advances, 2014, 4, 5080-5084. (三区)

授权专利:

7.孙文武，吴滨，邓婷婷。一类三环核苷酸类似物及其合成方法和应用。专利号：ZL 202111667205.1

6.孙文武，吴滨，邓婷婷，谢宜兵，马世杰，黄洁。一类内源性核苷M₁dG及其衍生物的合成方法及其应用。专利号：ZL 202111683273.7

5.孙文武，吴滨，邓婷婷，谢宜兵，马世杰，黄洁。一类脂肪链取代的三环核苷衍生物及其合成方法和应用。专利号：ZL202111683272.2

4.孙文武，吴滨，邓婷婷，谢宜兵，马世杰，黄洁。阿昔洛韦类三环核苷衍生物及其合成方法和应用。专利号：ZL202111683261.4

3.孙文武，吴滨，邓婷婷，谢宜兵，马世杰，黄洁。氨基酸取代的阿昔洛韦类三环核苷衍生物及其合成方法和应用专利号：ZL202111683242.1

2.吴滨，孙文武，曹沛，赵金华，杨莲。N-喹啉基取代的内酰胺类化合物及其药物组合物和合成方法与应用。专利号：ZL201310428596.0

1.吴滨，孙文武。一种beta-内酰胺化合物的合成方法。专利号：ZL201310549472.8